KMID : 1188320150090030318
|
|
Gut and Liver 2015 Volume.9 No. 3 p.318 ~ p.331
|
|
Gut Microbiota as Potential Orchestrators of Irritable Bowel Syndrome
|
|
Sean M.P. Bennet
Lena Ohman Magnus Simren
|
|
Abstract
|
|
|
Irritable bowel syndrome (IBS) is a multifactorial functional disorder with no clearly defined etiology or pathophysiology. Modern culture-independent techniques have improved the understanding of the gut microbiota¡¯s composition and demonstrated that an altered gut microbiota profile might be found in at least some subgroups of IBS patients. Research on IBS from a microbial perspective is gaining momentum and advancing. This review will therefore highlight potential links between the gut microbiota and IBS by discussing the current knowledge of the gut microbiota; it will also illustrate bacterial-host interactions and how alterations to these interactions could exacerbate, induce or even help alleviate IBS.
|
|
KEYWORD
|
|
Irritable bowel syndrome, Microbiota, Immunity, Dysbiosis, Probiotics
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|